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Compared to the TBI+Saline group (B), tPA treatment (C) significantly increased newborn mature neurons identified with BrdU/NeuN double immunofluorescent staining in the DG 35 days post injury. The bar graph (D) shows the number of DCX-positive cells. Scale bar = 25 µm. *p<0.05 vs TBI+Saline. Data represent mean ± SD. n = 8 (rats/ group).
