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. Author manuscript; available in PMC: 2014 Sep 3.
Published in final edited form as: Addict Biol. 2011 Aug 4;17(2):351–364. doi: 10.1111/j.1369-1600.2011.00357.x

Table 3.

Bioinformatics of ethanol and withdrawal-responsive genes in the nucleus accumbens.

Change Gene symbol (gene name) Proposed function P values
Circadian rhythms
↓ Car2 (Carbonic anhydrase 2) Circadian oscillations 2.3E-05
↓ Arntl (Aryl receptor nuclear translocator-like) Transcription factor 1.7E-04
↑ Car4 (Carbonic anhydrase 4) Circadian oscillations 3.5E-04
↑ Dbp (D site albumin promoter binding protein) Circadian oscillations 3.7E-04
↑ Per3 (period homolog 3) Rhythmic behavior 3.7E-04

P values indicate the level of significance in gene expression as determined by significance of analysis microarrays and the proposed function as determined by GeneMesh. Arrows indicate the direction (up- or down-regulation) of changes in gene expression.