Table 3. De-regulated miRNAs and their target genes from RNA-Seq.

mRNAs are predicted as targets of up- or down-regulated miRNAs. TargetScan-predicted miRNA-mRNA pairs showing negative correlation in expression profile were selected.

Down-regulated miRNAs	Up-regulated target genes
mmu-mir-148a	ARL6IP1, ARPP19, ATP2A2, CCNA2, CSF1, EGR2, ERLIN1, ERRFI1, FIGF, GADD45A, GMFB, ITGA5, KLF4, KLF6, LIMD2, MAFB, NFYA, PDIA3, PHIP, PPP1R10, PPP1R12A, PTPN14, RAI14, RSBN1L, SERPINE1, SIK1, SLC2A1, TMEM127, TMSB10, TMSB4X
mmu-mir-411	APOLD1, SPRY4
mmu-mir-136	RYBP, ARL10, GLIPR2, UGGT1

Up-regulated miRNAs	Down-regulated target genes
mmu-mir-34a/c	DAB2IP, DMWD, EVI5L, FAM107A, MAZ, SPEG, TFRC, TTC19
mmu-mir-92b	COL1A2, DAB2IP, G3BP2, HOXC11, LBX1, NFIX, PKDCC, PRKAB2
mmu-mir-132	ACTR3B, AMD1, GPD2, HBEGF, KBTBD13, KCNJ12, PRRT2, SREBF1, TLN2
mmu-mir-146a	IRAK1, TLN2
mmu-mir-152	EML2, GPCPD1, NFIX, RPH3AL, SH3KBP1, TFRC, TRAK1, UCP3
mmu-mir-155	DUSP7, G3BP2
mmu-mir-185	DAB2IP, FAM134C, SYNM, TMEM233
mmu-mir-203	APBB2, CACNG7, FKBP5, GDAP1, HBEGF, KCNC1, SIX5, TMEM182
mmu-mir-206	DMPK, G3BP2, GPD2, KCTD13, MKL1, SLC16A3, SPEG
mmu-mir-215	KLHL23