Table 1. Metabolic and cardiovascular variables.
Variable | WKY | FFR | SHR | FFHR | FFHR+V | |
Fasting glucose (mmol/L) | 4.88±0.1 | 6.44±0.2* | 5.0±0.2 | 6.5±0.2*∧ | 4.6±0.1** | |
Fasting triglycerides (mmol/L) | 0.8±0.0 | 1.9±0.0* # | 1.0±0.0 | 1.9±0.1* # | 1.0±0.2** | |
HOMA (µU/mLinsulin×mmol/L glucose)/22.5 | 4.00±0.2 | 11.0±0.1* # | 7.1±0.15* | 15.1±0.5* #∧ | 4.1±0.5** | |
Area under glucose tolerancetest curve (mmol/L/90 min) | 881±64 | 1352±21* # | 1300±35* | 1909±51* #∧ | 801±67** | |
HDL Cholesterol (mg/dl) | 21.5±0.3 | 13.2±0.4* # | 19±1,0* | 11.6±1,5* #∧ | 20.2±1.3** | |
High-sensitivity C reactiveProtein (mg/dL) | 1.5±0.1 | 3.5±0.0 | 3.1±0.1 | 4.5±0.1* #∧ | 1.01±0.3** | |
Systolic bloodpressure (mmHg) | ||||||
Baseline | 105±3 | 102±1.0 | 103±1 | 105±3 | 105±2 | |
6 weeks | 110±1.0 | 129±2.0* | 165±2* | 172±3* # | 170±3* | |
12 weeks | 112±1.3 | 139±3.0* | 178±1* # | 185±2* #∧ | 160±1.5** |
The above values correspond to metabolic and cardiovascular variables. Symbols indicate:
*p<0.001 vs. WKY;
∧p<0.001 vs. SHR;
p<0.01 vs. FFR.
**vs. FFHR.