Table 2. Oxidative stress and morphometric variables.
Variable | WKY | FFR | SHR | FFHR | FFHR+V |
NAD(P)H oxidase activity(counts/min/mg tissue) | 40.5±6 | 133±5* | 160±9.1* # | 297±9.1* #∧ | 42±9.1*∧** |
Arterial eNOS activity(dpm/mg/prot/min) | 85.0±2 | 60.1±2.6* | 80.0±2.1 | 56.4±5.7* #∧ | 86.4±1.1** |
TBARS (µmol/L) | 1±0.1 | 2.2±0.1* | 1.69±0.1* | 2.8±0.1* #∧ | 1.03±0.6#∧** |
Relative heart weight(mg/100 g body weight) | 225±4 | 290±4* | 330±1.8* # | 400±4* #∧ | 302±6** |
Myocardiocyte area (µm2) | 1682±69 | 2066±57* | 2222±78* # | 3242±55* #∧ | 1788±34** |
Lumen/media relationshipmesenteric arteries | 13.9±0.3 | 10.2±0.5* | 8.9±0.6* # | 8.45±0.2* # | 13.8±4** |
The above values correspond to oxidative stress and morphometric variables. Symbols indicate:
*p<0.001 vs WKY;
∧p<0.001 vs SHR;
p<0.01 vs FFR.
**vs FFHR.