Table 3. Cytokine release profiles on different experimental models.
Cytokinea | Relative levelsb | Array Locationc | Fold increase for control group (WKY)d | |||
SHR | FFR | FFHR | FFHR+V | |||
CINC-2 | H | E1-2 | 1.18 | 1.10 | 2.42 | 2.35 |
CINC-3 | H | F1-2 | 1.34 | 1.30 | 2.74 | 2.67 |
CNTF | - | G1-2 | ∼ | ∼ | ∼ | ∼ |
Fractalkine | - | H1-2 | ∼ | ∼ | ∼ | ∼ |
GM-CSF | - | A4-5 | ∼ | ∼ | ∼ | ∼ |
INF-γ | H | B3-4 | 5.00 | 4.50 | 5.90 | 5.40 |
IL-1α | - | C3-4 | ∼ | ∼ | ∼ | ∼ |
IL-1β | - | D3-4 | ∼ | ∼ | ∼ | ∼ |
IL-4 | - | E3-4 | ∼ | ∼ | ∼ | ∼ |
IL-6 | - | F3-4 | ∼ | ∼ | ∼ | ∼ |
IL-10 | - | G3-4 | ∼ | ∼ | ∼ | ∼ |
LIX | - | H3-4 | ∼ | ∼ | ∼ | ∼ |
Leptin | H | A5-6 | 1.16 | 1.33 | 2.10 | 1.07 |
MCP-1 | H | B5-6 | 1.25 | NC | 4.00 | 1.02 |
MIP-3α | H | C5-6 | 1.16 | 1.33 | 3.91 | 3.80 |
β-NGF | H | D5-6 | 2.40 | 2.40 | 3.50 | 3.53 |
TIMP-1 | H | E5-6 | 2.60 | 1.52 | 2.50 | ∼ |
TNF-α | H | F5-6 | 3.19 | 1.10 | 3.35 | ∼ |
VEGF | H | G5-6 | 2.50 | NC | 3.05 | 1.05 |
Name of cytokine.
Relative levels: -, undetectable; H, high: L, low.
See Figure 3 for the location of the duplicate spots in the matrix.
When the control “∼” symbol was used to indicate an approximation of zero, the values indicate the fold increase vs. WKY (control group). NC, no change (less than or equal to the fold change in the WKY group).