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. 2014 Sep 3;9(9):e106769. doi: 10.1371/journal.pone.0106769

Figure 2. HPLC chromatograms of the metabolite of nifedipine (NIF) catalyzed by recombinant CYP3A29.

Figure 2

(A) NIF standard. (B) Oxidized nifedipine (ONIF) standard. (C) NIF incubated with Sf9 microsomes containing the recombinant CYP3A29 at 37°C for 30 min in the presence of NADPH-generating system. (D) NIF incubated with Sf9 microsomes free of the recombinant CYP3A29 at 37°C for 30 min in the presence of NADPH-generating system. (E) NIF incubated with Sf9 microsomes containing the recombinant CYP3A29 at 37°C for 30 min in the absence of NADPH-generating system.