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. 2014 Sep 3;9(9):e106764. doi: 10.1371/journal.pone.0106764

Figure 2. H. hepaticus infection is necessary for increased liver pathology and preneoplastic lesions in FXR KO mice.

Figure 2

A) Mean hepatitis index (HI) ± SD is shown for each experimental group (**P<0.01). Representative liver sections from B) sham-treated WT (HI = 0) and H. hepaticus-infected FXR KO mice showing C) typical (HI = 1.5) and D) severe (HI = 6.5) hepatitis. H&E-stain, bar  = 100 µm. E) Mean FCA count ± SD is shown for each experimental group (*P<0.05). Examples of F) eosinophilic and G) clear cell foci from H. hepaticus-infected FXR KO mice (outlined by arrows; H&E-stain, bar  = 600 µm).