Table 2. Results of haplotype analysis in anti-CCP negative RA patients in association with CV events.

Variable		HR (95% CI)	p
	Age at RA diagnosis (by each year)	1.08 (1.06–1.10)	<0.001
	Hypertension	0.98 (0.63–1.51)	0.929
	Diabetes mellitus	1.58 (1.01–2.45)	0.043
	Obesity	1.22 (0.78–1.89)	0.390
	Dyslipidemia	1.27 (0.84–1.93)	0.254
	Smoking	1.12 (0.85–1.48)	0.417
Haplotypes (rs3134063, rs2073618, rs3134069)		HR (95% CI) *	p *
	TCA	1 (reference)	-
	TGA	0.94 (0.55–1.60)	0.825
	CCA	1.09 (0.68–1.76)	0.724
	CGA	0.54 (0.31–0.95)	0.032

CCP: cyclic citrullinated protein/peptide antibodies; CI: confidence interval; CV: cardiovascular; HR: hazard ratios; RA: rheumatoid arthritis.

*Adjusted for sex, age at RA diagnosis and traditional CV risk factors (hypertension, diabetes mellitus, dyslipidemia, obesity, and smoking habit).