Figure 5. Lung host defense defect in Myeloid-Cftr−/− mice.

Myeloid-Cftr−/− mice and Cftr^fl10 mice were infected with the agarose-embedded PsA at the lethal dose of (5×10⁶ cfu) by lung intubation. Casualties were recorded and survival curves traced. The log-rank test was performed to check statistical difference in survival between the Cftr^fl10 mice (n = 34) and the myeloid-Cftr−/− mice (n = 35). Double asterisks mean significant difference (p<0.01).