Table 3.

Differences of non-physicians performing flexible sigmoidoscopy with respect to outcome measures stratified by procedure indication and study design.

	Polyp detection rate % (95% CI)	Adenoma detection rate % (95% CI)	Colorectal cancer detection rate % (95% CI)	Adverse event rate (per 1,000 procedures) (95% CI)
Procedure indication
Colorectal screening
Non-physiciana	19.5 (18.5–20.6)	6.7 (6.1–7.4)	0.4 (0.3–0.9)	0.2 (0.04–0.9)
Mid-level	22.9 (21.5–24.4)	7.2 (6.4–8.2)	0.3 (0.06–0.9)	0 (0–1.0)
Nurse	14.8 (13.5–16.3)	6.1 (5.2–7.1)	0.4 (0.2–0.7)	0.4 (0.09–2.1)
Diagnostic
Non-physician	9.7 (9.1–10.2)	1.6 (1.4–2.0)	1.5 (1.3–1.7)	0.2 (0.05–0.7)
Mid-level	43.3 (37.4–49.3)	---	3.6 (2.1–5.9)	0 (0–8.9)
Nurse	8.9 (8.4–9.4)	1.6 (1.4–2.0)	1.4 (1.2–1.7)	0.2 (0.05–0.7)
Study design
Observational
Non-physician	12.6 (12.1–13.1)	3.8 (3.5–4.2)	1.3 (1.1–1.5)	0.2 (0.03–0.5)
Mid-level	24.5 (23.1–25.9)	7.2 (6.4–8.2)	1.3 (0.7–2.0)	0 (0–0.9)
Nurse	9.4 (8.9–9.9)	2.6 (2.3–2.9)	1.3 (1.1–1.5)	0.2 (0.04–0.6)
Randomized controlled trial
Non-physician	19.7 (16.9–22.8)	6.4 (4.8–8.5)	1.0 (0.4–2.0)	1.4 (0.03–7.6)
Mid-level	---	---	---	---
Nurse	19.7 (16.9–22.8)	6.4 (4.8–8.5)	1.0 (0.4–2.0)	1.4 (0.03–7.6)

^aNon-physician includes mid-level and nurse providers.