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. Author manuscript; available in PMC: 2014 Sep 3.
Published in final edited form as: IEEE Rev Biomed Eng. 2012 Dec 10;6:143–155. doi: 10.1109/RBME.2012.2232651

Fig. 4.

Fig. 4

Schematic representation of the “multimodal” approach in which minimal models of glucose-insulin regulation (e.g., Bergman [118]) and cardiovascular autonomic control (e.g., Blasi et al. [138]) can be employed along with measures derived from polysomnography and dual-energy Xray absorptiometry to establish functional relationships that link autonomic and metabolic function with obesity and severity of sleep-disordered breathing.