Table 1.
Intraindividual variability of hemostatic factors in men and women
| Women | Men | ||||
|---|---|---|---|---|---|
| Premenopausal (n=39) |
Postmenopausal (n=18) |
<40 years (n=30) |
> 40 years (n=16) |
||
| Age, y: Mean ± SD | 31.0 ± 8.2 | 57.5 ±7.8 | 28.5 ± 5.5 | 50.1 ± 6.8 | |
| Age, y: Range: | 22-51 | 43-67 | 22-39 | 41-65 | |
| BMI, kg/m2 Mean ± SD | 23.8 ± 3.4 | 25.7 ± 3.6 | 24.5 ± 2.8 | 25.2 ± 3.4 | |
| BMI, kg/m2 Range: | 17.3-29.8 | 18.8-32.1 | 18.5-30.8 | 18.8-30.9 | |
| Fibrinogen (mg/dl) |
mean a | 277 ± 16 | 326 ± 27 | 241 ± 16 | 284 ± 20 |
| variance b | 656 ± 88 | 827 ± 184 | 754 ± 130 | 459 ± 108 | |
| SD c | 25.6 | 28.8 | 27.5 | 21.4 | |
| CV (%) d | 9.2 | 8.8 | 11.4 | 7.6 | |
| Factor VII (%) | mean | 81 ± 6 | 97 ± 9 | 88 ± 7 | 91 ± 7 |
| variance | 37 ± 5 | 124 ± 27 | 31 ± 5 | 23 ± 5 | |
| SD | 6.04 | 11.1 | 5.57 | 4.78 | |
| CV (%) | 7.4 | 11.8 | 6.3 | 5.2 | |
| square root PAI-1 (ng/ml) |
mean | 2.4 ± 0.6 | 3.2 ± 0.8 | 2.7 ± 0.6 | 2.9 ± 0.8 |
| variance | 0.47 ± 0.06 | 0.55 ± 0.12 | 0.68 ± 0.12 | 0.29 ± 0.06 | |
| SD | 0.684 | 0.734 | 0.825 | 0.537 | |
| CV (%) | 28.5 | 23.4 | 30.1 | 18.4 | |
a
Estimate of the mean ± 1.96 standard errors (provides an approximate 95% confidence interval)
b
Estimate of residual intra-individual variance ± 1.96 standard errors (provides an approximate 95% confidence interval)
c
Standard deviation (SD) computed as the square root of the estimate of intra-individual variance.
d
Coefficient of variation (CV) computed as 100% × ( SD / mean ).