Skip to main content
. Author manuscript; available in PMC: 2014 Sep 4.
Published in final edited form as: Pharmacol Ther. 2012 Nov 16;138(1):1–17. doi: 10.1016/j.pharmthera.2012.11.002

Fig. 1. Dietary Inhibitors of Histone Modifications.

Fig. 1

Figure shows the representation of histone modifications (acetylation and deacetylation) by the phytochemicals derived from different food source. Phytochemicals like EGCG, genistein and curcumin play important role in inhibition of histone acetylation by inactivating histone acetyl transferase enzyme. Some other phytochemicals like sulforaphane, curcumin, genistein, phenyl isothiocynate, organosulfur compound, resveratrol and indol-3-carbinol inhibits the deacetylation of relaxed chromatine by inactivating histone deacetylase enzyme. There are several other phytochemicals that alter histone modifications which are not covered in this figure.