Table 4. Univariate analysis of OS and DFS in patients with ccRCC (months, mean ± SE).

Variable	n	Overall survival time	P	Disease-free survival time	P
Gender
Female	35	85.647±5.428	0.435	81.369±6.339	0.296
Male	54	82.408±7.128		78.919±7.546
Age, years
≤55	50	85.289±5.364	0.141	80.235±5.888	0.224
>55	39	80.583±7.627		77.429±8.166
Tumor size (cm)
≤4	15	113.000±4.714	0.003	107.442±6.919	0.015
>4	74	62.831±2.823		59.125±2.999
Tumor pathology stage
pT1-pT2	67	109.409±5.706	0.002	105.564±6.668	0.006
pT3-pT4	22	61.803±3.016		57.605±3.199
Grading
G1	23	101.421±7.149	0.003	97.042±7.829	0.022
G2	30	79.333±6.647		79.519±6.059
G3	24	57.177±3.935		48.145±3.686
G4	12	39.175±3.140		37.023±4.098
Lymph node metastasis
pNx	21	61.590±4.182	0.024	61.572±4.648	0.036
pN0	55	95.946±6.365		90.654±6.870
pN1/2	13	51.496±6.478		47.138±8.417
Vascular invasion
No	80	90.184±5.859	0.007	89.374±5.706	0.003
Yes	9	50.000±7.751		45.667±9.858
Tobacco smoking
No	32	88.905±7.336	0.668	81.334±8.117	0.825
Yes	57	76.277±4.170		73.948±4.376
DNMT1 expression
Positive	50	59.166±3.918	0.002	57.427±4.390	0.026
Negative	39	99.020±6.433		93.495±6.885

OS, overall survival; ccRCC, clear cell renal cell carcinoma.