Table 1. Pathological and clinical features of 37 primary DLBCL patients.
Patients | n | % |
---|---|---|
Age (year) | ||
<60 | 17 | 46 |
≥60 | 20 | 54 |
Laterality | ||
Left | 10 | 27 |
Right | 22 | 59 |
Bilateral | 5 | 14 |
Stage | ||
I | 22 | 59 |
II | 9 | 24 |
III | 1 | 3 |
IV | 5 | 14 |
IPI | ||
0-1 | 28 | 76 |
≥2 | 9 | 24 |
Histology* | ||
GCB | 4 [33] | 12 |
Non-GCB | 29 [33] | 88 |
BCL-2+ | 22 [25] | 88 |
Ki67 | ||
<50% | 3 [27] | 11 |
50%-<90% | 19 [27] | 70 |
≥90% | 5 [27] | 19 |
Radiotherapy | 22 | 59 |
Contralateral testis alone | 8 | 22 |
Contralateral testis plus abdominal lymphnodes | 14 | 37 |
Chemotherapy | ||
Doxorubicin-contained | 31 | 84 |
Rituximab-contained | 17 | 46 |
Etoposide-contained | 7 | 19 |
CNS prophylaxis | 20 | 54 |
Intrathecal methotrexate/cytarabine | 16 | 43 |
Intravenous methotrexate | 4 | 11 |
Treatment modalities | ||
Surgery alone | 3 | 8 |
Chemotherapy alone | 1 | 2 |
Surgery + radiotherapy | 3 | 8 |
Surgery + chemotherapy | 11 | 30 |
Surgery + chemotherapy + radiotherapy | 19 | 52 |
IPI, international prognostic index; BCL-2, b-cell leukemia-2; GCB, grminal center B cell like lymphoma; non-GCB, non-grminal center B cell like lymphoma; CNS, central nervous system; DLBCL, diffuse large B-cell lymphoma. *, GCB type was evaluated in 33 patients, BCL-2 was assessed in 25 patients and Ki67 was detected in 27 patients.