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. 2014 Feb 21;31(8):2010–2021. doi: 10.1007/s11095-014-1303-9

Table I.

Plasma Octreotide Levels of Cynomoglus Monkeys Orally Dosed for 9-months with 20 mg Octreotide Acetate and Oily Suspension in Enteric-coated Capsules

Sex PK parameters Treatment days
1 180 270
Male Cmax (ng/mL) 22 ± 6 39 ± 35 30 ± 18
AUC0-t (h × ng/mL) 49 ± 13 84 ± 74 68 ± 40
Female Cmax (ng/mL) 15 ± 4 13 ± 3 42 ± 14
AUC0-t (h × ng/mL) 34 ± 9 28 ± 7 92 ± 31
Total Cmax (ng/mL) 19 ± 4 26 ± 13 36 ± 11
AUC0-t (h × ng/mL) 42 ± 8 56 ± 29 80 ± 25

Results expressed as arithmetic mean ± SE (n = 5 per gender)