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Micturition patterns in CIE mice as assessed by filter paper assay. A: representative images of voiding spots in a mouse with CIE (CSS of 3) taken every week for 4 wk. B: number of small size urine spots (<1.0 cm) in mice with a CSS of 2 or 3 during the progression of demyelination in the CNS. C: analysis of large urine spots (≥1.0 cm) in the same animals. *P ≤ 0.05 vs. baseline.
