Fig. 11.

Deletion of PKCε promotes receptor-interacting protein kinase (RIP) degradation/inactivation in cerulein-induced pancreatitis. Western blot analysis of pancreas tissue lysate using antibodies against RIP to measure the protein levels of the protein in cerulein (CR) pancreatitis at indicated times. The same samples were used to rerun gel and blotted with ERK1/2 antibody to confirm equal protein loading. Samples were run in a single gel but were not continuous, as indicated by a line between lanes. Bar figures are the quantification of these protein band densities that were compared with saline (S) control. Values are means ± SE (n = 2–3) for each condition. *P < 0.05 vs. WT mice with CR at the same time point as indicated; #, the 2 bars are compared statistically. Numbers to the right of the gels are protein size (kDa).