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Tritiated ryanodine binding studies confirm the presence of RyR in mouse and human acinar cells. Specific ryanodine binding in mouse brain, mouse pancreas, and human acinar cells was calculated by subtracting samples incubated with excess cold ryanodine (40 μM) plus 2.5–20 nM [3H] ryanodine from samples incubated with [3H] ryanodine alone.
