Table 2.
Time-updated adjusted associations between predictors and altered taste perception, and change in taste perception.*
| aOR (95% CI) for worsening taste perception (vs persistence of normal taste perception) in setting of normal initial taste perception (n=3207 pt years) | aOR (95% CI) for persistently altered taste perception (vs improving taste perception) in setting of altered initial taste perception (n=2035 pt years) | |
|---|---|---|
| Age; per 10 years | 1.03 (0.97 – 1.10) | 1.00 (0.99 – 1.01) |
| Female | 1.06 (0.89 – 1.27) | 0.95 (0.77 – 1.16) |
| Black race | 1.18 (0.99 – 1.40) | 0.89 (0.73 – 1.10) |
| Vintage; per 1 year longer on dialysis | 0.97 (0.96 – 0.99) | 0.97 (0.95 – 0.99) |
| Catheter as access | 1.15 (0.96 – 1.38) | 0.97 (0.79 – 1.20) |
| Change in access type≠ | 1.11 (0.76 – 1.63) | 1.09 (0.78 – 1.53) |
| Diabetes | 0.99 (0.82 – 1.18) | 1.10 (0.90 – 1.34) |
| Congestive heart failure | 1.01 (0.86 – 1.20) | 0.72 (0.60 – 0.87) |
| Ischemic heart disease | 1.17 (0.98 – 1.39) | 0.99 (0.81 – 1.22) |
| Remote cerebro-vascular disease┼ | 0.89 (0.73 – 1.09) | 0.75 (0.60 – 0.95) |
| Inter-current cerebro-vascular event# | 1.67 (0.94 – 2.98) | 2.28 (1.33 – 3.89) |
| Peripheral vascular disease | 1.09 (0.90 – 1.33) | 0.91 (0.74 – 1.13) |
| Tobacco use | 1.05 (0.89 – 1.24) | 1.01 (0.83 – 1.22) |
| Alcohol abuse | 1.13 (0.89 – 1.42) | 1.18 (0.93 – 1.50) |
| Drug abuse | 0.86 (0.62 – 1.18) | 1.23 (0.85 – 1.77) |
| eKt/V; per 0.1 unit | 0.90 (0.62 – 1.18) | 1.03 (0.97 – 1.04) |
| Change in eKt/V; per 0.1 unit increase from prior# | 1.05 (0.98 – 1.03) | 0.90 (0.96 – 1.02) |
| Ultrafiltration; per 1 L | 0.96 (0.89 – 1.03) | 0.97 (0.89 – 1.05) |
| Change in ultrafiltration; per 1 L increase from prior# | 0.98 (0.90 – 1.07) | 1.02 (0.94 – 1.12) |
*
All estimates are adjusted for other variables in the table; robust variance estimates used to account for within-subject clustering. Separate, analogous models were fit for patient-intervals beginning with normal and altered taste perception (index year). Predictors were considered as of start of the index year. Outcomes defined based on evolution in taste perception from index year to subsequent year.
┼
In preceding current interval
#
During the interval leading up to index.