Fig. 7. Foci of differentiated neurons at the cerebellar surface of 3 week old miR-17∼92cKO; Ptch1^+/−; Cdkn2c^+/− mice.

Cerebella from 3 week old Ptch1^+/−; Cdkn2c^+/− mice wild type (A–E) or null (F–J) for the miR-17∼92 cluster were stained with H&E (A,B,F,G), an antibody against Ki67 (C,H), NeuN (D,I), and GABA(A) receptor α6 subunit (GABARa6) (E,J). Enlarged views of boxed areas (A,F) are presented in panels B–E and G–J, respectively. PNL (arrow, B–E) is composed of densely packed undifferentiated and proliferating neurons. Foci of differentiated, non-proliferating neurons (arrows, G–J). Scale bars: 500 µm (A,F), 100 µm (B,G).