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. 2010;2(1):35–54.

Table III. Recommended Endocrine Therapy.

FTM-transsexual individuals

Suppression of original sex hormones Replacement of the hormones of desired sex*

Oral lynestrenol 5 mg daily (Orgametril®) Testosterone ester 125-250 mg every two weeks IM (Sustanon®)
Oral medroxyprogesterone acetate 5-10 mg daily Testosterone Undecanoate 1000 mg every 10-12 weeks
(Provera®, Farlutal®) IM (Nebido®)
GnRH-analogue: triptoreline 3.75 mg (Decapeptyl®) Testosterone 100 mg transdermally daily (Androgel®,
IM monthly or goserelin 3.6 mg (Zoladex®) SC monthly Testim®, Testogel®)

MTF-transsexual individuals
Suppression of original sex hormones Replacement of the hormones of desired sex*

Oral cyproterone acetate 50-100 mg daily (Androcur®) Oral 17β-estradiol valerate 2-4 mg daily (Progynova®)
Transdermal estradiol 1.5-3 mg daily (Estreva®, Oestrogel®)

Transdermal 17β-estradiol 50-100 µg daily (Climara®,
Dermestril®, Vivelle Dot®)

Bold: substances preferred by the Ghent Gender Team.

*: continued after SRS.