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. Author manuscript; available in PMC: 2014 Sep 4.
Published in final edited form as: J Cell Physiol. 2012 Mar;227(3):1042–1051. doi: 10.1002/jcp.22821

FIGURE 8. Schematic representation of the mechanisms of action of TWEAK in skeletal muscle.

FIGURE 8

The role of NF-κB and various proteolytic systems and a potential cross-talk between them in TWEAK-treated myotubes leading to myotube atrophy is depicted in this figure. Broken line indicates relatively weaker connection.