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. Author manuscript; available in PMC: 2014 Sep 4.
Published in final edited form as: Cell Stem Cell. 2009 Jul 2;5(1):54–63. doi: 10.1016/j.stem.2009.05.003

Figure 2. Heat Map of Microarray Assays of Mouse Lungs after I.v. Infusion of hMSCs.

Figure 2

About 2 × 106 hMSCs were infused i.v., and lung RNA was recovered 10 hr later for assays on both mouse-specific and human-specific microarrays (Affymetrix, Santa Clara, CA). Data were filtered for cross-hybridization (CV > 0.5 and call > 33%), analyzed with the Microarray Suite 5.0 program, and normalized to a value of 1 and variance of 3 SD (+3, red; 3, blue). Gene ontology categories of genes are indicated. The number of genes with expression differences is indicated in the boxes.

(A) Assay on mouse-specific chip.

(B) Assay of same RNA on human-specific chip. Symbols: con, lung from control mouse; hMSCs con, sample of hMSCs added to lung from control mouse before extraction of RNA; hMSCs i.v., sample from mouse lung 10 hr after i.v. infusion of hMSCs.