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. Author manuscript; available in PMC: 2014 Sep 4.
Published in final edited form as: Expert Opin Biol Ther. 2014 May 16;14(9):1271–1283. doi: 10.1517/14712598.2014.920319

Figure 2. Group responses of HIS-mice engrafted with different donor stem cells.

Figure 2

In this experiment, actively immunized groups of HIS-mice prepared from different donors were vaccinated with 100 µg of TT-SNC with alum adjuvant at the beginning of week 1 and a booster dose of the same vaccine at week 3. Serum from each animal was collected at week 6 and pooled serum from each group was tested by ELISA for anticocaine IgG antibody. The group results are shown for each vaccine condition, expressed as the percent response compared to the donor 1 response arbitrarily defined as 100%. HIS-mice: Humanized immune system mice.