TABLE 1.

Serum hemoglobin, iron and transferrin levels before and after restorative proctocolectomy (RPC)

Point of control	Parameter	n	% below normal vs. ref value	% above normal vs. ref value	Mean ± SEM	P value vs. precolectomy	Reference level
Precolectomy	Hemoglobin	63	44	5	123.46 ± 2.85 g/L		130–165 g/L (Men)
Ileostomy	Hemoglobin	48	18	4	137.96 ± 2.34 g/L	0.004	115–145 g/L (Women)
Loop ileostomy	Hemoglobin	76	12	5	138.84 ± 1.56 g/L	0.0001
6 months	Hemoglobin	75	11	5	139.27 ± 1.85 g/L	0.0001
12 months	Hemoglobin	65	11	9	141.74 ± 1.77 g/L	0.0001
18 months	Hemoglobin	55	7	5.5	140.16 ± 2.0 g/L	0.0001
24 months	Hemoglobin	50	12	2	140.6 ± 2.09 g/L	0.0001
36 months	Hemoglobin	30	14	7	140.2 ± 3.01 g/L	0.001
Precolectomy	Iron (Fe)	55	49	0	10.78 ± 0.99 μmol/L		9–38 μmol/L (Men)
Ileostomy	Iron (Fe)	37	23	0	12.95 ± 1.03 μmol/L	0.33	5–35 μmol/L (Women)
Loop ileostomy	Iron (Fe)	57	16	4	17.54 ± 1.53 μmol/L	0.0003
6 months	Iron (Fe)	68	15	0	15.57 ± 1.05 μmol/L	0.005
12 months	Iron (Fe)	61	11	0	16.34 ± 1.04 μmol/L	0.0005
18 months	Iron (Fe)	49	21	0	15.47 ± 1.04 μmol/L	0.005
24 months	Iron (Fe)	46	18	0	15.07 ± 1.11 μmol/L	0.01
36 months	Iron (Fe)	31	16	0	17.45 ± 1.40 μmol/L	0.01
Precolectomy	Transferrin	15	0	0	2.53 ± 0.35 g/L		2.1–3.60 g/L
Ileostomy	Transferrin	16	0	6	2.9 ± 0.26 g/L	0.34
Loop ileostomy	Transferrin	14	0	14	3.55 ± 0.41 g/L	0.66
6 months	Transferrin	14	0	0	2.58 ± 0.48 g/L	0.34
12 months	Transferrin	16	0	0	2.3 ± 0.32 g/L	0.32
18 months	Transferrin	15	0	0	2.82 ± 0.16 g/L	0.33
24 months	Transferrin	12	0	0	3.0 ± 0.6 g/L	0.70
36 months	Transferrin	11	0	0	2.4 ± 0.25 g/L	0.35

Precolectomy, levels the night prior to total colectomy and ileostomy; Ileostomy, levels night prior to pouch construction; Loop ileostomy, levels prior to closure of diverting loop ileostomy; months, levels of functional pouch after diverting loop ileostomy closure.

Adapted and published (2001) with permission from the Karolinska Institute data base³⁶