Table 1.
Reactivity with seroconversion panels.
| Panel ID | Luminex assay | USDA licensed HIV tests |
European test |
|||||
|---|---|---|---|---|---|---|---|---|
| S/Coa | Anti-HIV EIAb S/Co |
HIV Agc S/Co |
PCRd Copy number |
Western blote Band pattern |
3rd Generation EIAf S/Co |
EIAg S/Co |
||
| PRB929 | PRB929-01 | 0.72 | 0.20 | 0.50 | NEG | No Bands | 0.20 | 0.10 |
| PRB929-02 | 0.81 | 0.20 | 0.50 | NEG | No Bands | 0.20 | 0.20 | |
| PRB929-03 | 1.36 | 0.20 | 0.90 | POS | No Bands | 0.30 | 0.20 | |
| PRB929-04 | 16.02 | 0.20 | 13.40 | POS | No Bands | 0.20 | 0.30 | |
| PRB929-05 | 132.44 | 0.90 | >22.7 | POS | No Bands | 0.70 | 0.20 | |
| PRB929-06 | 93.94 | >16.3 | >22.7 | POS | f24, f160 | 12.50 | 2.10 | |
| PRB929-07 | 9.96 | >16.3 | >22.7 | POS | 24, 120, 160 | >13.0 | 4.50 | |
| PRB950 | PRB950-01 | 0.55 | 0.20 | 0.50 | BLD | No Bands | 0.20 | 1.90 |
| PRB950-02 | 1.13 | 0.20 | 0.70 | 7×104 | No Bands | 0.20 | 2.10 | |
| PRB950-03 | 6.04 | 0.20 | 3.30 | 5×105 | No Bands | 0.20 | 2.20 | |
| PRB950-04 | 8.47 | >15.5 | 4.10 | 5×105 | No Bands | 16.40 | 7.00 | |
| PRB917 | PRB917-01 | 0.70 | 0.20 | 0.40 | NEG | No Bands | 0.10 | 0.30 |
| PRB917-02 | 6.19 | 0.20 | 3.90 | POS | No Bands | 0.10 | 0.40 | |
| PRB917-03 | 41.46 | 0.30 | 21.60 | POS | No Bands | 0.10 | 0.40 | |
| PRB917-04 h | 6.60 | 12.70 | POS | No Bands | 0.20 | 1.00 | ||
| PRB917-05 | 1.87 | 10.20 | 2.40 | POS | 24.00 | 7.90 | 4.50 | |
| PRB917-06 | 1.55 | 10.80 | 1.60 | POS | 24.00 | 13.60 | 5.70 | |
| PRB917-07 h | 9.20 | 0.40 | POS | 24, f65, 160 | 30.40 | 7.90 | ||
Data obtained with the Luminex assay expressed as signal/cut-off (S/Co), where cut-off is defined as the mean background value + 3 standard deviations; a S/Co above 1 (in bold) is considered positive.
Data provided as S/Co by BBI/SeraCare using the Abbott Anti-HIV 1-2 enzymatic immunoassay.
Data provided as S/Co by BBI/SeraCare using the Abbott Anti-HIV1 antigen immunoassay.
Data provided as positive or negative values or number of copies per ml of serum using the Roche HIV-1 for panels PRB929 and PRB917 and the Roche amplicor assay for PRB 950.
Confirmatory western blots from Ortho/Cambridge, data interpreted using ASTPHLD/CDC criteria (MMWR, vol. 38, S-7, 1989). Faintly stained bands are indiacted by “f”.
Data provided as S/Co by BBI/SeraCare using the 3rd generation enzymatic immunoassay fromAbbott 3rd Generation Plus for panels PRB929 and PRB950 and Diagnostic Pasteur HIV 1/2 for panel PRB917.
Data provided as S/Co by BBI/SeraCare using the 3rd Generation enzymatic immunoassay from Biotest HIV 1/2 for panels PRB929 and PRB950 and Murex Wellcozyme HIV 1/2 for panel PRB 917.
Samples no longer available.