Figure 1.
Age-severity relationship as measured by retroillumination photography among individuals affected with Fuchs Corneal Dystrophy. In Tangier, the number of guttae increase by approximately 10% each year (p<0.001). At age 60, the maximum age in the FCD1 sample, the number of guttae in affected eyes associated with FCD1 is 39.6 times higher (p<0.001) and FCD2 is 13.5 times higher (p<0.001) than in eyes associated with Tangier. Data points represent affected individuals for whom retroillumination photographs were acquired.