. Author manuscript; available in PMC: 2014 Sep 4.

Published in final edited form as: J Child Neurol. 2011 Apr 25;26(6):675–682. doi: 10.1177/0883073810395141

Table 5.

Recommended Second-Line Preventive Therapies

Multiple Sclerosis	Score^a	Neuromyelitis Optica	Score^a
Scheduled corticosteroids	203	Rituximab	180
Pulse intravenous immunoglobulin	189	Pulse intravenous immunoglobulin	163
Plasma exchange	125	Plasma exchange	160
Natalizumab	124	Scheduled corticosteroids	154
Cyclophosphamide	119	Azathioprine	147
Azathioprine	112	Mycophenolate	106
Mycophenolate	109	Cyclophosphamide	99
Rituximab	107	Mitoxantrone	64
Mitoxantrone	82	Natalizumab	36

Respondents were asked to rank order their treatment preference given failure of first-preventive therapy. Scores consisted of the sum of all responses, with higher points given for preferred treatments.