. Author manuscript; available in PMC: 2015 Aug 1.

Published in final edited form as: Lancet Respir Med. 2014 May 19;2(8):611–620. doi: 10.1016/S2213-2600(14)70097-9

Table 2.

Comparison of Key Biomarker Values (Pre-Randomization) Between ARMA and ALVEOLI Cohorts

Biomarker^*	ARMA Cohort	ALVEOLI Cohort	p-value
Protein C (% control)	47 (32–66)	78 (45–122)	< .001
Plasminogen activator inhibitor-1 (ng/ml)	70 (40–138)	61 (30–144)	.002
Interleukin-6 (pg/ml)	264 (109–766)	238 (93–741)	.26
Interleukin-8 (pg/ml)	43 (20–93)	40 (16–98)	0.001
Soluble tumor necrosis factor receptor-I (pg/ml)	3255 (2128–5600)	4265 (2599–8448)	< .001
Soluble intercellular adhesion molecule-1 (ng/ml)	627 (345–1038)	924 (605–1385)	< .001
Surfactant Protein D (ng/ml)	84 (40–162)	101 (50–218)	.004
Von Willebrand Factor antigen (% control)	284 (173–436)	398 (247–624)	< .001

Data shown as median (interquartile range)