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Chromosome 2 complementation restores activin-induced transactivation. (A) The pARE-Luc reporter was transfected into cells before stimulation with activin. (B) Northern blotting for c-Myc expression, known to be down-regulated by activin, was performed using a generated c-Myc probe. A GAPDH probe was used as a loading control, and the relative expression of c-Myc to GAPDH is shown in the bar graph.
