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. Author manuscript; available in PMC: 2014 Sep 4.
Published in final edited form as: ILAR J. 2012;53(2):114–125. doi: 10.1093/ilar.53.2.114

Figure 1.

Figure 1

Influences of diet and husbandry regimen on total neoplasia incidences in AB wild-type fish at 22 months of age. Replicate tanks of fish fed each of 2 diets, OTD (semi-purified Oregon Test Diet) or COM (mixture of commercial diets containing fish meal) and reared at each of 3 sites, FT-A (flow-through system design, location A), FT-B (flow-through system design, location B), or RC-C (recirculating system with fluidized sand biofiler). Tumor incidences were significantly higher in the recirculating system compared to flow through systems, regardless of diet (P=0.0000, chi-square with Yates’ correction; red asterisk). Also, diet did not significantly influence tumor incidences at the flow-through sites (P>0.24 for FT-A and P>0.7 for FT-B), but did significantly influence tumor incidences in the recirculating system (P<0.0001; blue asterisk).