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Exploiting endogenous IgG binding for targeted delivery. An antibody (Herceptin) that is known to bind the Her-2 receptor was adsorbed to lipoplexes (20% DOTAP/80% cholesterol), and used to transfect Her-18 cells that overexpress this receptor. No enhancement of transfection was observed. Each bar represents the mean transfection of 5 individual wells, and the error bars represent the standard errors.
