Skip to main content
. Author manuscript; available in PMC: 2014 Sep 4.
Published in final edited form as: Ther Deliv. 2013 Apr;4(4):453–462. doi: 10.4155/tde.13.16

Table I.

Proteins Associated with Lipoplex Formulations. Proteins associated with each formulation were identified by MALDI/MS. The 50:50 formulation adsorbed many additional proteins, but only those in common with the other formulations are listed for comparison. The total quantity of adsorbed protein on each formulation is also shown, as is the diameter (nm) of each lipoplex before and after incubation in fetal calf serum (FCS).

24PC 22PC 20PC 18PC 16PC 14PC 20:80 50:50
Unidentified (3,530 Da) - - - x x x x x
Unidentified (12,600 Da) - - - x x x - -
Unidentified (13,300 Da) x x x - - - - x
Cationic trypsin (25,768 Da) - - - - - - x x
Immunoglobin gamma-2 C region (35,878 Da) x x x - - - x x
Immunoglobin gamma-1 C region (36,083 Da) x x x - - - x x
Alpha-2-HS-glycoprotein (38,394 Da) x x x - - - - x
Albumin (69,248 Da) - - - x x x x x
Collagen alpha-1 chain (93,594 Da) x x x - - - - -
mg protein/g lipid 185.5 107.6 155.1 131 250.3 229.6 76.4 181.1
diameter before FCS 174.5 178.4 162.4 204.7 293.4 290.5 209.1 204.6
diameter after FCS 189.7 182.6 158.5 535.4 419 546.5 217.3 219.6