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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Eur Respir J. 2014 May 29;44(2):341–350. doi: 10.1183/09031936.00216013

Table 6.

Most significant genome-wide association results for the overlap of COPD and asthma in the meta-analysis of NHW and AA.

CHR SNP Gene/nearest gene Reference Allele OR CI P Value
14 rs6574978 GPR65 T 1.59 0.29,1.76 1.18×10−7
14 rs8004567 GPR65 A 0.61 −0.68,0.79 1.18×10−7
14 rs1441809 GPR65 A 1.58 0.29,1.76 1.58×10−7
14 rs3759712 GALC C 0.63 −0.63,0.80 1.80×10−7
14 rs6574977 GPR65 A 0.64 −0.62,0.81 3.16×10−7
14 rs2165570 GPR65 T 0.67 −0.56,0.82 3.95×10−7
14 rs6574980 LOC283587 T 1.60 0.29,1.78 4.48×10−7
14 rs7157094 GPR65 T 0.63 −0.64,0.81 7.00×10−7
8 rs6471581 CYP11B2 T 0.66 −0.57.0.83 7.74×10−7
8 rs4736359 CYP11B2 T 1.51 0.25,1.67 7.79×10−7