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Release of KLH contained in NPs in 10%human serum (pH 7.4) at 37°C. All NPs exhibited a prolonged release of KLH. PK NPs showed a burst release of KLH between 8 and 10 h. LPK displayed a delayed release profile, in which the largest percentage release occurred between 16 and 24 h. The extent of release was also dependent on the composition and charge of the NPs.
