Table 1. Neutralization titers against CHIKV-S27 and CHIKV-IND/NL10.

Animal #	Day 0	Day 21	Day 63	Day 0	Day 21	Day 63	Status after challenge
MVA Vaccine	Challenge virus
6KE1	CHIKV-S27			CHIKV-IND/NL10
Mouse 1	<10	<10	10	<10	<10	20	survived
Mouse 2	<10	<10	20	<10	<10	20	survived
Mouse 3	<10	<10	10	<10	<10	10	survived
Mouse 4	<10	<10	10	<10	<10	10	survived
Mouse 5	<10	<10	<10	<10	<10	<10	dead
Mouse 6	<10	<10	<10	<10	<10	10	survived
Mouse 7	<10	<10	<10	<10	<10	<10	survived
Mouse 8	<10	<10	10	<10	<10	10	dead
MVA Vaccine	Challenge virus
E3E2	CHIKV-S27			CHIKV-IND/NL10
Mouse 1	<10	10	20	<10	10	20	survived
Mouse 2	<10	<10	20	<10	10	20	survived
Mouse 3	<10	<10	20	<10	10	10	survived
Mouse 4	<10	<10	20	<10	10	20	survived
Mouse 5	<10	10	10	<10	10	20	survived
Mouse 6	<10	10	10	<10	10	10	survived
Mouse 7	<10	<10	10	<10	<10	10	survived
Mouse 8	<10	10	20	<10	10	20	survived
MVA Vaccine	Challenge virus
6KE1E3E2	CHIKV-S27			CHIKV-IND/NL10
Mouse 1	<10	10	80	<10	20	80	survived
Mouse 2	<10	10	80	<10	10	80	survived
Mouse 3	<10	10	160	<10	20	160	survived
Mouse 4	<10	10	80	<10	10	80	survived
Mouse 5	<10	20	40	<10	20	80	survived
Mouse 6	<10	10	40	<10	20	40	survived
Mouse 7	<10	20	80	<10	20	160	survived
Mouse 8	<10	20	40	<10	20	40	survived
MVA Vaccine	Challenge virus
Wildtype	CHIKV-S27			CHIKV-IND/NL10
Mouse 1	<10	<10	<10	<10	<10	<10	dead
Mouse 2	<10	<10	<10	<10	<10	<10	dead
Mouse 3	<10	<10	<10	<10	<10	<10	dead
Mouse 4	<10	<10	<10	<10	<10	<10	dead
Mouse 5	<10	<10	<10	<10	<10	<10	dead
Mouse 6	<10	<10	<10	<10	<10	<10	dead
Mouse 7	<10	<10	<10	<10	<10	<10	dead
Mouse 8	<10	<10	<10	<10	<10	<10	dead