Table 2. Constants and parameters in the stochastic model.
Parameter | Value | Description |
varied | Niche group size | |
10 | Niche carrying capacity of stem cells | |
Eq. (2) | MPCR | |
varied | MPCR parameter (exponent) | |
varied | MPCR parameter (multiplier) | |
Eq. (1) | Feedback from , on activity | |
Eq. (1) | Feedback from , on differentiation | |
Eq. (1) | Feedback from , on activity | |
2.5 | symmetric division (self-renewal) rate | |
1 | asymmetric division (self-renewal) rate | |
0.001 | (symmetric) differentiation rate | |
0.1 | differentiation rate | |
0.1 | differentiation rate | |
0.1 | differentiation rate | |
0.25 | multiplication rate | |
0.004 | death rate | |
0.02 | death rate | |
0.001 | death rate | |
0.001 | death rate | |
0.028 | death rate | |
0.01 | death rate | |
Feedback parameter of in | ||
Feedback parameter of in | ||
Feedback parameter of in | ||
Feedback parameter of in | ||
Feedback parameter of in | ||
Feedback parameter of in |
*Note: these parameters change depending on the niche group size, in order to maintain the same stable state at homeostasis, thus allowing equal comparison between them.