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. 2014 Sep 4;8(9):e3099. doi: 10.1371/journal.pntd.0003099

Figure 2. MiR-146a expression in nerve and skin biopsies, and according to patients' genotype (rs2910164).

Figure 2

MiR-146a mature form expression was analyzed in nerve (A, B) and skin (C, D) specimens by real-time stem-loop RT-PCR after total RNA extraction. RNU48 expression was used to normalization. (A) Analysis was performed comparing the levels of miR-146a expression in nerve biopsies (NL = not leprosy, n = 7/Leprosy, n = 12). (B) MiR-146a expression stratified by rs2910164/G>C genotype, GG (n = 8) and GC (n = 7). The data show mean ± SEM (*p = 0.0099; and **p = 0.0401) (C) Results show neither difference of miR-146a expression in skin biopsies according to clinical forms (PB = 37 and MB = 17), nor by genotype stratification (GG = 10; GC = 22; CC = 4) (D).