Figure 3. Hierarchical agglomerative cluster analysis of expression patterns of Danio rerio embryos tothree whole sediments and sediment extracts and 11 substances.
(Yang et al. 2007; Acrylamide: 71 mg/l; Arsenic: arsenic (III) oxide, 79 mg/l; BDE: 2,2′4,4′-tetrabromo-diphenyl ether solution 47, 38.9 mg/l; CA: 4-chloroaniline, 50 mg/l; Cd: cadmium chloride, 5 mg/l; DDT: 1,1-bis-(4-chlorphenyl)-2,2,2-trichlorethane 15 mg/l; Lead: lead (II) chloride, 2.8 mg/l; PCB: Aroclor 1254, 33 mg/l; TBHQ: tert-butylhydroquinone, 1.7 mg/l; TCDD: 2,3,7,8-tetrachlorodibenzo-p-dioxin, 500 ng/l; VA: valproic acid, 50 mg/l). The cells are coloured according to the fold-change of a gene under a certain treatment. Blue segments represent genes with a strong decrease in the abundance of the corresponding transcript, red segments represent genes with a strong increase in the abundance of the corresponding transcript and green segments denote unaffected genes.