. 2014 May 23;136(24):8766–8771. doi: 10.1021/ja503593n

Table 1. Sulfimidation Activity and Selectivity of BM3 Variants Using Substrates and Reaction Conditions Shown^a.

graphic file with name ja-2014-03593n_0004.jpg

entry	enzyme	TTN	er
1	P411_BM3-CIS T438S	300	74:26
2	P450_BM3-CIS T438S	7	nd
3	P411_BM3-CIS A268T T438S	19	nd
4	P411_BM3-H2-5-F10	140	29:71
5	P411_BM3-H2-A-10	84	57:43
6	P411_BM3-H2-4-D4	32	70:30
7	P450_BM3	10	nd
8	P411_BM3	11	nd
9	P450_BM3-T268A	19	nd
10	P411_BM3-T268A	17	nd
11	P411_BM3-CIS I263A T438S	320	18:82

“P411” denotes Ser-ligated (C400S) variant of cytochrome P450_BM3.^13b,13c Variant IDs and specific amino acid substitutions in each can be found in the Table S1. TTN = total turnover number, er = enantiomeric ratio, nd = not determined.

Table 1. Sulfimidation Activity and Selectivity of BM3 Variants Using Substrates and Reaction Conditions Showna.

Table 1. Sulfimidation Activity and Selectivity of BM3 Variants Using Substrates and Reaction Conditions Shown^a.