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Pharmacokinetic Parameters for ARAP 22
| IV infusion | value |
|---|---|
| Cmax IV (ng/mL) | 3404 |
| Co (ng/mL) | 4152 |
| T1/2 (min) | 74 |
| Tlast (min) | 480 |
| Clast (ng/mL) | 2.3 |
| MRT (min) | 31 |
| Cl (mL/min/kg) | 80.8 |
| Vdss (L/kg) | 2.7 |
| AUC 0–480 IV (min·ng/mL) | 61660 |
| AUCinf IV (min·ng/mL) | 61906 |
|
| |
| PO administration | value |
|
| |
| Cmax PO (ng/mL) | 1767 |
| Tmax PO (min) | 5 |
| Tlast (min) | 480 |
| Clast (min) | 34 |
| T1/2 (min) | 179 |
| MRT (min) | 145 |
| AUC0–480 PO (min·ng/mL) | 79441 |
| AUCinf PO (min·ng/mL) | 88183 |
| Mean Fpo last (%) | 49 |
