Table 8. ALK mutations detected by both Sanger sequencing and IT-PGM.
Case Number | Coding DNA | Amino acid | Depth of Coverage (x) | Variant allele frequency (%) |
11011 | c.3522C>G | p.F1174L | 1992 | 50.45 |
145808 | c.3522C>A | p.F1174L | 782 | 15.09 |
70309 | c.3824G>A | p.R1275Q | 897 | 20.07 |
180713 | c.3824G>A | p.R1275Q | 1536 | 41.99 |
184213 | c.3522C>A | p.F1174L | 1996 | 56.21 |