Figure 1. Serum urea levels in WT, collagen XV and/or XVIII deficient mice after renal I/R.

WT mice showed an increased serum urea levels at day 5 after I/R while all collagen mutant mice (Col15a1^−/− and Col18a1^−/− p<0.05, and Col15a1^−/−×Col18a1^−/− p<0.01) had significantly lower serum urea levels compared to WT at this time point. The results are expresses as serum urea mmol/l ± SEM. *: p<0.05, **: p<0.01.