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. 2014 Sep 4;9(9):e106751. doi: 10.1371/journal.pone.0106751

Table 2. Risk factors for ≥4-fold increase in hemagglutination inhibition (HI) titer against A/Mexico/4108/2009(H1N1) from 2009 to 2010 among cohort subjects, Kamphaeng Phet, Thailand; odds ratios calculated by binary logistic regression.

Variables Total N A/Mexico/4108/2009(H1N1)
≥4-fold Unadjusted OR (95% CI) Adjusted OR (95% CI)
increase
N (%)
Birth Year
>1968 195 25 (34.2) 2.8 (1.5–5.3) 2.2 (1.1–4.3)
1958–1968 249 31 (42.5) 2.7 (1.4–5) 2.5 (1.3–4.8)
≤1957 337 17 (23.3) Reference
Gender
Male 318 29 (39.7) 1 (0.6–1.6) -
Female 463 44 (60.3)
Indoor Water
Yes 528 59 (80.8) 2.1 (1.2–3.9) -
No 253 14 (19.2)
Geographical Region
Phran Kratai District 298 44 (60.3) 2.7 (1.7–4.4) 2.6 (1.5–4.5)
Mueng District 483 29 (39.7) Reference
Swine Exposure
Yes 87 7 (9.6) 0.8 (0.4–1.9) -
No 694 66 (90.4)
Developed a respiratory illness in the last 12 monthsa
Yes 423 44 (60.3) 1.3 (0.8–2.2) -
No 357 29 (39.7)
A/Brisbane/59/2007(H1N1)
Positive 143 19 (26) 1.7 (1.0–2.9) -
Negative 638 54 (74)
A/SW/Gent/7625/99(H1N2)
Positive 211 48 (65.8) 6.4 (3.8–10.7) 5.8 (3.4–10.0)
Negative 570 25 (34.2) Reference
A/SW/Lutol/3/2000(H1N1)
Positive 26 11 (15.1) 8.2 (3.6–18.6) 3.7 (1.5–9.6)
Negative 755 62 (84.9) Reference

Abbreviation: OR, odds ratio; CI, confidence interval.

a

Covariate has some missing values.