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. 2010 Sep;2(2):104–109.

Table 1 . Enzyme elevation according to gender, coexisting medical problems and hepatotoxic drug consumption.

Group with hepatotoxicity (%) Group with non-hepatotoxicity (%) p -value
Gender (female) 25 16.2 0.89
Liver disease* 50 22.7 0.09
Congestive heart failure 41.7 22.7 0.16
Alcohol consumption 1.8 0.5 0.42
Cigarette smoking 12.5 24.4 0.38
Diabetes mellitus 30.4 23 0.44
Hypertriglyceridemia 26.8 23 0.69
Hypercholesterolemia 32.3 22.4 0.44
Hepatotoxic drug consumption** 31.3 14 0.001
Use of chloroquine 22.8 26.9 0.69

* Autoimmune hepatitis, non-alcoholic steatohepatitis, liver congestion due to congestive heart failure and mitral stenosis, Gilberts’ disease, autoimmune hepatitis and liver hemangioma.

** NSAID, Sulfasalazine, Angiotensin Converting Enzyme inhibitors and Angiotensin Receptor Blockers, Statins and Omeprazole. (Prednisolone has been used in all of the patients).