Table 1. Antiplasmodial and transmission blocking activities of the CLK inhibitors.

Compound	Class	IC50 (Malstat) [µM]	IC50 (EIA) [µM]
KH-CARB10	oxo-β-carboline	7.2±2.40	14.0±3.72
KH-CARB11	oxo-β-carboline	6.1±1.09	15.8±0.84
KH-CARB13xHCl	oxo-β-carboline	4.4±1.84	13.8±6.22
C-117	aminopyrimidine	7.5±2.76	67.5±13.03
gea-27	aminopyrimidine	5.2±0.35	154.2±56.43
CHX	antiseptic	0.6±0.20	19.8±0.93
Chloroquine	4-aminoquinoline	0.04±0.013	N/A