Table 1. Expression level (optical density of immunoreactive signal; arbitrary unit) of calgranulin B and positivity rate of FOBT according to the type of colorectal disease.
| Calgranulin B | FOBT | |||||
| Development set | Median | Range | P-value | Positive | P-value | |
| Cancer (n = 81) | 2557.5 | 0.0–5432.1 | <0.001* | 42/81 (51.9%) | <.0001 | |
| T stage | T1 (n = 14) | 1813.2 | 0.0–4804.9 | 0.314 | 1/14 (7.1%) | 0.001 |
| T2 (n = 10) | 2998 | 0.0–5181.2 | 6/10 (60.0%) | |||
| T3 (n = 47) | 2557.5 | 0.0–5432.1 | 26/47 (55.3%) | |||
| T4 (n = 10) | 3112.2 | 1507.3–4926.3 | 9/10 (90.0%) | |||
| Site | ||||||
| Right (n = 21) | 2566.7 | 0.0–5288.8 | 0.863 | 11/21 (52.4%) | 0.955 | |
| Left (n = 60) | 2522.5 | 0.0–5432.1 | 31/60 (51.7%) | |||
| Controls ( n = 51) | 0 | 0.0–4448.9 | – | 1/51 (1.9%) | – | |
| Validation set | ||||||
| Cancer (n = 94) | 2968.6 | 0.0–4608.1 | <0.001* | 52/94 (55.3%) | <.0001 | |
| T stage | T1 (n = 10) | 2577.5 | 0.0–3300.3 | 0.113 | 2/10 (20.0%) | 0.019 |
| T2 (n = 8) | 2329.8 | 0.0–3359.5 | 2/8 (25.0%) | |||
| T3 (n = 59) | 3069.8 | 0.0–4608.1 | 37/59 (62.7%) | |||
| T4 (n = 17) | 2942.4 | 0.0–4585.7 | 11/17 (64.7%) | |||
| Site | ||||||
| Right (n = 25) | 2842.2 | 0.0–3985.8 | 0.674 | 13/25 (52.0%) | 0.697 | |
| Left (n = 69) | 2992.5 | 0.0–4608.1 | 39/69 (56.5%) | |||
| Controls ( n = 100) | 0 | 0.0–3955.3 | – | 0/100 | – | |
FOBT, fecal occult blood test (100 ng/mL stool).
*by the Wilcoxon rank sum test.