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. 2014 Sep 4;9(9):e106182. doi: 10.1371/journal.pone.0106182

Table 2. Cross-validated sensitivity at the specificity closest to 90% and the AUC and pAUC of the two models (all in %).

Sensitivity* Specificity** AUC Partial AUC***
Development set
Model 1: AGE + FOBT 75.31 90.2 89.52 6.65
Model 2: AGE + FOBT + CALB 83.95 90.2 92.05 7.02
Development set (Leave-one-out cross-validation)
Model 1: AGE + FOBT 75.31 90.2 87.78 5.62
Model 2: AGE + FOBT + CALB 82.72 90.2 89.81 5.70
Validation set
Model 1: AGE + FOBT 79.79 90 90.65 7.34
Model 2: AGE + FOBT + CALB 79.79 90 92.74 7.71

AUC. Area under the curve; pAUC, partial area under the curve, FOBT. Fecal occult blood test; CALB, calgranulin B.

*Sensitivity when the specificity of the model developing samples is set at closest to 90%.

**Observed specificity closest to 90%.

***Partial AUC for specificities range from 90% to 100%.